The Buffalo Bills want to take another step up the AFC food chain in 2021 and that starts with a Week 1 home showdown against one of the long-time gatekeepers of the conference, the Pittsburgh Steelers.
NFL betting odds have Buffalo giving 6.5 points to Pittsburgh at Orchard Park, where they knocked off the Steelers 26-15 as a 2-point favorite last December. While many believe Pittsburgh’s era of excellence has run out, this spread sitting under the touchdown shows the Steelers plenty of respect.
Check out our free NFL picks and predictions for Steelers at Bills on September 12.